Synthesis, characterisation and multi-modal intracellular mapping of cisplatin nano-conjugates

Chem Commun (Camb). 2023 May 23;59(42):6395-6398. doi: 10.1039/d3cc00925d.

Abstract

The synthesis of nanocarriers for the delivery of the antitumor drug cisplatin is reported. Multimodal-imaging consisting of surface enhanced Raman scattering and laser ablation inductively coupled plasma time of flight mass spectrometry was used to visualise the intracellular uptake of both the nanocarrier and drug.

MeSH terms

  • Antineoplastic Agents*
  • Biological Transport
  • Cisplatin*
  • Spectrum Analysis, Raman

Substances

  • Cisplatin
  • Antineoplastic Agents