BAF155 promotes cardiac hypertrophy and fibrosis through inhibition of WWP2-mediated PARP1 ubiquitination

Affiliations

• ¹ Department of Cardiology, First Hospital of China Medical University, Shenyang, Liaoning, China.
• ² Key Laboratory of Reproductive and Genetic Medicine, National Health Commission, China Medical University, Shenyang, Liaoning, China.
• ³ State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.
• ⁴ Institute of School of Basic Medicine, China Medical University, Shenyang, Liaoning, China.
• ⁵ Center of Reproductive Medicine, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
• ⁶ Department of Cardiology, First Hospital of China Medical University, Shenyang, Liaoning, China. yxsun@cmu.edu.cn.
• ⁷ Key Laboratory of Environmental Stress and Chronic Disease Control and Prevention, Ministry of Education, China Medical University, Shenyang, Liaoning, China. yxsun@cmu.edu.cn.