Risk factors of hip joint structural changes following pedicle subtraction osteotomy for ankylosing spondylitis-related thoracolumbar kyphosis: a minimum two-year observation

Eur Spine J. 2023 Jul;32(7):2293-2302. doi: 10.1007/s00586-023-07726-0. Epub 2023 May 8.

Abstract

Purpose: To determine the clinical- and surgical-related factors of hip joint structural changes in ankylosing spondylitis (AS) patients with thoracolumbar kyphosis who underwent PSO.

Methods: Hip involvement was assessed by the Bath Ankylosing Spondylitis Radiology Hip Index (BASRI-h) and defined by a score of at least 2. 52 patients with BASRI-h scores maintained and 78 patients with BASRI-h scores increased during follow-up were retrospectively reviewed. Clinical data were recorded. Radiological assessment was performed preoperatively, postoperatively, and at the final follow-up.

Results: No significant difference existed in age, gender and follow-up time between the groups, but earlier onset of AS, longer disease and kyphotic duration, and worse Bath Ankylosing Spondylitis Functional Index (BASFI) scores at the final follow-up were observed in patients with BASRI-h scores increased (P < 0.05). Besides, global kyphosis (GK), T1-pelvic angle (TPA), pelvic tilt (PT) and anterior pelvic plane angle (APPA) were always larger in patients with BASRI-h scores increased, accompanied with more sacral fixation (P < 0.05). Multivariate logistics regression showed that earlier onset of AS, longer kyphotic duration, larger preoperative GK, sacral fixation and larger APPA during follow-up were independent risk factors.

Conclusion: Earlier onset of AS and longer kyphotic duration were the clinical risk factors of hip joint structural changes in AS patients following PSO, while larger preoperative GK, sacral fixation in PSO and larger APPA during follow-up were the surgical-related factors. Surgeons should inform patients with risk factors of the possibility for severe hip joint structural changes after PSO.

Keywords: Ankylosing spondylitis; Hip joint structural changes; Pedicle subtraction osteotomy; Risk factors; Thoracolumbar kyphosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Hip Joint / diagnostic imaging
  • Hip Joint / surgery
  • Humans
  • Kyphosis* / diagnostic imaging
  • Kyphosis* / etiology
  • Kyphosis* / surgery
  • Lumbar Vertebrae / diagnostic imaging
  • Lumbar Vertebrae / surgery
  • Osteotomy / adverse effects
  • Retrospective Studies
  • Spondylitis, Ankylosing* / complications
  • Spondylitis, Ankylosing* / diagnostic imaging
  • Spondylitis, Ankylosing* / surgery
  • Thoracic Vertebrae / diagnostic imaging
  • Thoracic Vertebrae / surgery
  • Treatment Outcome