Pseudoangiomatous stromal hyperplasia of the breast, imaging and clinical perspective: A review

Breast Dis. 2023;42(1):147-153. doi: 10.3233/BD-220072.

Abstract

Pseudoangiomatous stromal hyperplasia (PASH) is a benign breast pathology, which most commonly presents incidentally along with other breast pathologies. The etiology and pathogenesis of PASH are still unknown; however, there is some evidence suggesting PASH is hormone dependent. The clinical history, presentation, and imaging appearance of PASH are variable. Clinically, PASH has a wide spectrum of presentations, from being silent to gigantomastia. On imaging, PASH demonstrates various benign to suspicious features. Here we summarize PASH's clinical presentation, histopathology, imaging features, and management.

Keywords: Breast ultrasound; PASH; breast MRI; mammography.

Publication types

  • Review

MeSH terms

  • Angiomatosis* / diagnostic imaging
  • Angiomatosis* / pathology
  • Breast / diagnostic imaging
  • Breast / pathology
  • Breast Diseases* / diagnostic imaging
  • Breast Diseases* / pathology
  • Breast Neoplasms* / diagnostic imaging
  • Breast Neoplasms* / pathology
  • Female
  • Humans
  • Hyperplasia / pathology

Supplementary concepts

  • Pseudoangiomatous stromal hyperplasia