Recent advances in the biomolecules mediated synthesis of nanoclusters for food safety analysis

Devaraj Sabarinathan; Arumugam Selva Sharma; Marimuthu Murugavelu; Balakrishnan Kirubasankar; Indhiradevi Balusamy; Zhang Han; Huanhuan Li; Quansheng Chen

doi:10.1016/j.heliyon.2023.e15655

Recent advances in the biomolecules mediated synthesis of nanoclusters for food safety analysis

Heliyon. 2023 Apr 20;9(5):e15655. doi: 10.1016/j.heliyon.2023.e15655. eCollection 2023 May.

Authors

Devaraj Sabarinathan^{1

2}, Arumugam Selva Sharma¹, Marimuthu Murugavelu¹, Balakrishnan Kirubasankar³, Indhiradevi Balusamy⁴, Zhang Han¹, Huanhuan Li¹, Quansheng Chen¹

Affiliations

¹ School of Food and Biological Engineering, Jiangsu University, Zhenjiang, PR China.
² Athenese Dx Pvt Ltd, Chennai, Tamilnadu, India.
³ Department of Energy Science, Sungkyunkwan University, Suwon, South Korea.
⁴ Department of Pediatrics, Kanchi Kamakoti Childs Trust Hospital, Chennai, India.

Abstract

The development of nanoclusters based on incorporating biomolecules like proteins, lipids, enzymes, DNA, surfactants, and chemical stabilizers creates a stable and high fluorescence bio-sensors promising future due to their high sensitivity, high level of detection and better selectivity. This review addresses a comprehensive and systematic overview of the recent development in synthesizing metal nanocluster by various strategized synthesis techniques. Significantly, the application of nanometal clusters for the detection of various food contaminants such as microorganisms, antibodies, drugs, pesticides, metal contaminants, amino acids, and other food flavors have been discussed briefly concerning the detection techniques, sensitivity, selectivity, and lower limit of detection. The review further gives a brief account on the future prospects in the synthesis of novel metal nanocluster-based biosensors, and their advantages, shortcomings, and potential perspectives toward their application in the field of food safety analysis.

Keywords: Drugs; Metal ions; Metal nanocluster; Microbes; Pesticides; Synthesis.

Publication types

Review