Renal primitive neuroectodermal tumor: A rare case with a good prognosis

Hanmin Chen; Yanmin Li; Qingming Zeng; Gengqing Wu

doi:10.3389/fsurg.2023.1180107

Renal primitive neuroectodermal tumor: A rare case with a good prognosis

Front Surg. 2023 Apr 19:10:1180107. doi: 10.3389/fsurg.2023.1180107. eCollection 2023.

Authors

Hanmin Chen¹, Yanmin Li¹, Qingming Zeng¹, Gengqing Wu¹

Affiliation

¹ Department of Urology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, China.

Abstract

Background: Renal primitive neuroectodermal tumor (rPNET) has the characteristics of a difficult preoperative diagnosis, a high degree of malignancy, easy early metastasis or postoperative recurrence, a poor prognosis, and so on. However, rPNET that has no metastasis before surgery can have a good survival prognosis only after radical surgical resection.

Methods: We report the case of a 14-year-old male patient with a renal tumor who underwent open radical left nephrectomy without radiotherapy or chemotherapy before or after surgery, as confirmed by postoperative pathological results. The prognosis was followed up by a regular review of the chest and whole abdomen on CT, hematuria analysis, renal function, and electrolytes according to the guidelines for renal cancer.

Results: Postoperative pathological results confirmed rPNET; no adjuvant radiotherapy or chemotherapy were performed after surgery; no tumor recurrence or metastasis were observed during the follow-up of nearly 5 years.

Conclusions: Despite the high degree of rPNET malignancy, patients without metastases before surgery can still obtain a good survival prognosis through timely radical surgery.

Keywords: chemoradiotherapy; good survival prognosis; radical surgery; rare case; renal primitive neuroectodermal tumor.