2-(3-Methyl-2-oxoquinoxalin-1-yl)- N-(4-methyl-phen-yl)acetamide

Mohcine Missioui; Abdulsalam Alsubari; Joel T Mague; El Mokhtar Essassi; Youssef Ramli

doi:10.1107/S2414314623003577

2-(3-Methyl-2-oxoquinoxalin-1-yl)- N-(4-methyl-phen-yl)acetamide

IUCrdata. 2023 Apr 21;8(Pt 4):x230357. doi: 10.1107/S2414314623003577. eCollection 2023 Apr.

Authors

Mohcine Missioui¹, Abdulsalam Alsubari², Joel T Mague³, El Mokhtar Essassi⁴, Youssef Ramli^{1

5}

Affiliations

¹ Laboratory of Medicinal Chemistry, Drug Sciences Research Center, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Morocco.
² Laboratory of Medicinal Chemistry, Faculty of Clinical Pharmacy, 21 September University, Yemen.
³ Department of Chemistry, Tulane University, New Orleans, LA 70118, USA.
⁴ Laboratory of Heterocyclic Organic Chemistry, Faculty of Sciences, Mohammed V University, Rabat, Morocco.
⁵ Mohammed VI Center for Research and Innovation (CM6), Rabat 10000, Morocco.

Abstract

The quinoxaline moiety in the title mol-ecule, C₁₈H₁₇N₃O₂, is not quite planar and the p-tolyl group is rotationally disordered over two nearly equally populated sets of sites. In the crystal, N-H⋯O and C-H⋯O hydro-gen bonds form chains extending along the b-axis direction. Due to the disorder of the p-tolyl rings, short C⋯C distances are observed between adjacent chains.

Keywords: amide; crystal structure; edge-to-edge π-interaction; hydrogen bond; quinoxaline.

Grants and funding

Funding for this research was provided by: National Science Foundation, Major Research Instrumentation Program (grant No. 1228232).