A unique ratiometric fluorescent probe for detection of SO2 derivatives in living cells and real food samples

Shifei Li; Lin Wang; Yanyan Ma; Weiying Lin

doi:10.1016/j.talanta.2023.124615

A unique ratiometric fluorescent probe for detection of SO₂ derivatives in living cells and real food samples

Talanta. 2023 Aug 1:260:124615. doi: 10.1016/j.talanta.2023.124615. Epub 2023 Apr 29.

Authors

Shifei Li¹, Lin Wang¹, Yanyan Ma², Weiying Lin³

Affiliations

¹ Institute of Fluorescent Probes for Biological Imaging, School of Chemistry and Chemical Engineering, School of Materials Science and Engineering, University of Jinan, Jinan, Shandong 250022, PR China.
² Shandong Provincial Key Laboratory of Marine Monitoring Instrument Equipment Technology, National Engineering and Technological Research Center of Marine Monitoring Equipment, Institute of Oceanographic Instrumentation, Qilu University of Technology (Shandong Academy of Sciences), Qingdao, Shandong, 266061, PR China.
³ Institute of Fluorescent Probes for Biological Imaging, School of Chemistry and Chemical Engineering, School of Materials Science and Engineering, University of Jinan, Jinan, Shandong 250022, PR China; Guangxi Key Laboratory of Electrochemical Energy Materials, Institute of Optical Materials and Chemical Biology, School of Chemistry and Chemical Engineering, Guangxi University, Nanning, Guangxi 530004, PR China. Electronic address: weiyinglin2013@163.com.

PMID: 37141822
DOI: 10.1016/j.talanta.2023.124615

Abstract

Abnormal levels of SO₂ in organisms can cause cardiovascular disease and respiratory allergies. In addition, the amount of SO₂ derivatives used as food preservatives is strictly controlled, and excessive addition can also be harmful to health. Therefore, it is essential to develop a highly sensitive method for the detection of SO₂ and its derivatives in biological systems and real food samples. In this work, a new fluorescent probe (TCMs) with high selectivity and sensitivity for the detection of SO₂ derivatives was reported. The TCMs could quickly identify SO₂ derivatives. It has been successfully used to detect exogenous and endogenous SO₂ derivatives. Furthermore, the TCMs has high sensitivity to SO₂ derivatives in food samples. Moreover, the prepared test strips could be evaluated for the content of SO₂ derivatives in aqueous solutions. This work provides a potential chemical tool to detect SO₂ derivatives in living cells and real food samples.

Keywords: Ratiometric fluorescent probe; Real food samples; SO(2) derivatives.

MeSH terms

Fluorescent Dyes* / chemistry
HeLa Cells
Humans
Mitochondria / chemistry
Sulfur Dioxide* / analysis
Water / chemistry

Substances

Fluorescent Dyes
Sulfur Dioxide
Water