Glaucoma in Uveitic Eyes: Long-Term Clinical Course and Management Measures

Ocul Immunol Inflamm. 2023 May 4:1-7. doi: 10.1080/09273948.2023.2202740. Online ahead of print.

Abstract

Background: The management of glaucoma in uveitis is challenging. A meticulous combination of anti-glaucoma and anti-inflammatory agents is often needed to control the intraocular pressure (IOP) and preserve the visual status in an otherwise blinding disease.

Aim: To study the clinical course and management of glaucoma in uveitic eyes.

Methods: A retrospective study analyzing the case records of patients over 12 years, referred for the management of uveitic glaucoma in the last two decades.

Results: The analysis of 582 uveitic glaucoma eyes of 389 patients was done, and the mean IOP at baseline was 25.89 (±13.1) mmHg. Non-granulomatous uveitis (102 eyes) was the most common diagnosis. Granulomatous uveitis was the most common diagnosis among the treatment failure eyes and in eyes requiring more than one surgical intervention for glaucoma.

Conclusion: An appropriate and adequate combination of anti-inflammatory and IOP-lowering therapy will lead to better clinical outcomes.

Keywords: Corticosteroids; drainage implants; glaucoma; immunosuppressants; trabeculectomy; uveitis.