Quantitative structural analysis of hemifacial microsomia mandibles in different age groups

Ziwei Zhang; Xiaojun Chen; Byeong Seop Kim; Wenqing Han; Yingjie Yan; Xuetong Wang; Xin Li; Yan Zhang; Gang Chai

doi:10.3389/fped.2023.1157607

Quantitative structural analysis of hemifacial microsomia mandibles in different age groups

Front Pediatr. 2023 Apr 17:11:1157607. doi: 10.3389/fped.2023.1157607. eCollection 2023.

Authors

Ziwei Zhang¹, Xiaojun Chen¹, Byeong Seop Kim¹, Wenqing Han¹, Yingjie Yan¹, Xuetong Wang¹, Xin Li¹, Yan Zhang¹, Gang Chai¹

Affiliation

¹ Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.

Abstract

Introduction: This study aims to quantitively analyze mandibular ramus and body deformities, assessing the asymmetry and progression in different components.

Methods: This is a retrospective study on hemifacial microsomia children. They were divided into mild/severe groups by Pruzansky-Kaban classification and into three age groups (<1 year,1-5 years, 6-12 years old). Linear and volumetric measurements of the ramus and the body were collected via their preoperative imaging data to compare between the different sides and severities, using independent and paired tests, respectively. The progression of asymmetry was assessed by changes in affected/contralateral ratios with age using multi-group comparisons.

Results: Two hundred and ten unilateral cases were studied. Generally, the affected ramus and body were significantly smaller than those on the contralateral side. Linear measurements on the affected side were shorter in the severe group. Regarding affected/contralateral ratios, the body was less affected than the ramus. Progressively decreased affected/contralateral ratios of body length, dentate segment volume, and hemimandible volume were found.

Discussion: There were asymmetries in mandibular ramus and body regions, which involved the ramus more. A significant contribution to progressive asymmetry from the body suggests treatment focus in this region.

Keywords: hemifacial microsomia; mandibular asymmetry; mandibular body; mandibular ramus; progression.

Grants and funding

This work was supported by Clinical Research Plan of SHDC (grant no. SHDC2020CR3070B); Shanghai Jiao Tong University School of Medicine Two-hundred Talent (grant no. 20161420); Clinical Research Program of 9th People's Hospital affiliated to Shanghai Jiao Tong university School of Medicine (grant no. JYLJ202108); Interdisciplinary Program of Shanghai Jiao Tong University (grant no. YG2022QN048); Shanghai Clinical Research Center of Plastic and Reconstructive Surgery supported by Science and Technology Commission of Shanghai Municipality (grant no. 22MC1940300).