OPTN/SRTR 2021 Annual Data Report: Lung

Maryam Valapour; Carli J Lehr; David P Schladt; Jodi M Smith; Rebecca Goff; Tatenda G Mupfudze; Kaitlin Swanner; Katrina Gauntt; Jon J Snyder

doi:10.1016/j.ajt.2023.02.009

OPTN/SRTR 2021 Annual Data Report: Lung

Am J Transplant. 2023 Feb;23(2 Suppl 1):S379-S442. doi: 10.1016/j.ajt.2023.02.009.

Authors

Maryam Valapour¹, Carli J Lehr², David P Schladt³, Jodi M Smith⁴, Rebecca Goff⁵, Tatenda G Mupfudze⁵, Kaitlin Swanner⁵, Katrina Gauntt⁵, Jon J Snyder⁶

Affiliations

¹ Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN; Department of Pulmonary Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH.
² Department of Pulmonary Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH.
³ Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN.
⁴ Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN; Department of Pediatrics, University of Washington, Seattle, WA.
⁵ Organ Procurement and Transplantation Network, United Network for Organ Sharing, Richmond, VA.
⁶ Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN; Department of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN; Department of Medicine, Hennepin Healthcare, University of Minnesota, Minneapolis, MN.

Abstract

The number of lung transplants has continued to decline since 2020, a period that coincides with the onset of the COVID-19 pandemic. Lung allocation policy continues to undergo considerable change in preparation for adoption of the Composite Allocation Score system in 2023, beginning with multiple adaptations to the calculation of the Lung Allocation Score that occurred in 2021. The number of candidates added to the waiting list increased after a decline in 2020, while waitlist mortality has increased slightly with a decreased number of transplants. Time to transplant continues to improve, with 38.0% of candidates waiting fewer than 90 days for a transplant. Posttransplant survival remains stable, with 85.3% of transplant recipients surviving to 1 year; 67%, to 3 years; and 54.3%, to 5 years.

Keywords: End-stage lung disease; Lung Allocation Score; lung transplant; organ allocation; revised Lung Allocation Score; transplant outcomes.

MeSH terms

COVID-19* / epidemiology
Graft Survival
Humans
Lung
Pandemics
Resource Allocation
Tissue Donors
Tissue and Organ Procurement*
Treatment Outcome
United States / epidemiology
Waiting Lists