Hollow covalent organic frameworks (COFs) have gained significant attention because of their specific properties, including enhanced surface-to-volume ratio, large surface area, hierarchical structure, highly ordered nanostructures, and excellent chemical stability. These intrinsic characteristics endow hollow COFs with fascinating physicochemical properties and make them highly attractive for widespread applications, such as catalysis, energy storage, drug delivery, therapy, sensing, and environmental remediation. This review focuses on the recent developments in the synthesis of hollow COFs and their derivatives. In addition, their practical applications in various fields are summarized. Finally, challenges and future opportunities in terms of their synthetic methodologies and practical applications are discussed. Hollow COFs are expected to play an important role in the future of materials science.
Keywords: advanced porous materials; core−shell; covalent organic frameworks; derivatives; dynamic covalent chemistry; hollow structure; morphology modulation; nanoarchitecture engineering.