Vitamin-based radiopharmaceuticals for tumor imaging

Med Oncol. 2023 May 2;40(6):165. doi: 10.1007/s12032-023-02031-8.

Abstract

Advances in nuclear medicine, such as single photon emission computed tomography (SPECT) and positron emission tomography (PET), are among the most sensitive methods that can be used in diagnostic imaging and radionuclide therapy with higher efficiency and reduced toxicity benefits. In order to improve the success of treatment, it is also important to develop methods that can be used when lesions can be detected at the earliest stages. Vitamins are macromolecules that play a crucial role in numerous biological processes in both animals and humans. Escalating development of vitamin-based radiopharmaceuticals for application in the diagnosis and treatment of cancers. In this review, we aimed to discuss about recent research utilizing radio-labeled vitamins for targeted tumor imaging.

Keywords: Cancer; PET-CT; SPECT; Vitamins.

Publication types

  • Review

MeSH terms

  • Humans
  • Neoplasms* / diagnostic imaging
  • Neoplasms* / radiotherapy
  • Positron-Emission Tomography
  • Radiopharmaceuticals*
  • Tomography, Emission-Computed, Single-Photon / methods
  • Vitamins

Substances

  • Radiopharmaceuticals
  • Vitamins