Reduction of double chin without surgery using ascorbic acid and ascorbyl-palmitate solution: a clinical study

Eur Rev Med Pharmacol Sci. 2023 Apr;27(3 Suppl):109-113. doi: 10.26355/eurrev_202304_31327.

Abstract

Objective: The purpose of the present clinical study is to assess the effectiveness of a lipolytic solution containing sodium salt of ascorbic acid at 0.24% and a surfactant agent at 0.020% ascorbyl-palmitate (SAP) for the treatment of double chin.

Patients and methods: A total of 10 healthy adult subjects affected by double chin (8 female and 2 male) were evaluated in the present investigation. The patients were admitted to a total of 4 sessions, with biweekly procedures, without no other active agents addiction.

Results: In all the subjects a reduction of the convexity of the chin after the treatment with SAP was observed. Improvement in submental appearance was achieved in 90% (9/10) of the patients. One patient did not see any improvement in submental appearance after two section treatments and withdrew from the treatment.

Conclusions: In conclusion, in the present study, a new adipocytolytic solution consisting of sodium ascorbate mixed with ascorbyl-palmitate was used with success as a surfactant agent for the treatment of double chin.

MeSH terms

  • Adult
  • Ascorbic Acid*
  • Chin
  • Female
  • Humans
  • Male
  • Palmitates
  • Pulmonary Surfactants*
  • Surface-Active Agents

Substances

  • 6-O-palmitoylascorbic acid
  • Ascorbic Acid
  • Surface-Active Agents
  • Pulmonary Surfactants
  • Palmitates