Comparison of patient-reported upper extremity disability following free flaps in head and neck reconstruction: A systematic review and meta-analysis

Head Neck. 2023 Jul;45(7):1832-1840. doi: 10.1002/hed.27375. Epub 2023 May 2.

Abstract

Background: Comparisons of patient-reported donor site morbidity based on the Disabilities in Arm, Shoulder, and Hand (DASH) instrument across upper trunk free flaps in head and neck surgery, including radial forearm (RFFF), osteocutaneous radial forearm (OCRFF), scapular tip (STFF), and serratus anterior (SAFF) free flaps, may help inform donor tissue selection.

Methods: In this meta-analysis, 12 studies were included and the primary outcome was average DASH score.

Results: The pooled DASH scores were 12.14 (95% CI: 7.40-16.88) for RFFF (5 studies), 17.99 (11.87-24.12) for OCRFF (2 studies), 12.19 (8.74-15.64) for STFF (3 studies), and 16.49 (5.92-27.05) for SAFF (2 studies) and were not significantly different.

Conclusions: Results suggest that patients generally function well, with minimal to mild donor site morbidity, when assessed at an average of 20 months after flap harvest. These results are based on few effects from primarily retrospective studies of fair quality, and further research is needed.

Keywords: Disabilities in Arm, Shoulder, and Hand; donor site morbidity; free flap; patient-reported outcome measures; upper extremity disability.

Publication types

  • Meta-Analysis
  • Systematic Review
  • Review

MeSH terms

  • Forearm / surgery
  • Free Tissue Flaps*
  • Humans
  • Patient Reported Outcome Measures
  • Radius / surgery
  • Retrospective Studies