A novel method to accurately recreate in vivo loads and kinematics in computational models of the knee

Comput Methods Biomech Biomed Engin. 2024 May;27(7):860-866. doi: 10.1080/10255842.2023.2206934. Epub 2023 May 1.

Abstract

Despite availability of in vivo knee loads and kinematics data, conventional load- and displacement-controlled configurations still can't accurately predict tibiofemoral loads from kinematics or vice versa. We propose a combined load- and displacement-control method for joint-level simulations of the knee to reliably reproduce in vivo contact mechanics. Prediction errors of the new approach were compared to those of conventional purely load- or displacement-controlled models using in vivo implant loads and kinematics for multiple subjects and activities (CAMS-Knee dataset). Our method reproduced both loads and kinematics more closely than conventional models and thus demonstrates clear advantages for investigating tibiofemoral contact or wear.

Keywords: Knee joint; boundary conditions; contact mechanics; in vivo; simulation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomechanical Phenomena
  • Computer Simulation*
  • Humans
  • Knee / physiology
  • Knee Joint* / physiology
  • Models, Biological
  • Weight-Bearing / physiology