There is still the need to lower LDL-c, although the use of statins, ezetimibe and proprotein convertase subtilisin/kexin type 9. Patients with atherosclerotic cardiovascular disease and/or familial hypercholesterolaemia are treated with statins at maximum tolerated dose, with or without further lipid-lowering drugs, but very often, we can't reach the goal, so bempedoic acid treatment lead to a significant reduction in low-density lipoprotein cholesterol, in different groups of patients, with a favourable safety profile.
Keywords: Bempedoic acid; Cardiovascular disease; LDL-cholesterol; Statin intolerance.
© The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology.