There have been rare reports of dilated cardiomyopathy from chronic use of phentermine/topiramate, although very limited data are available. Phentermine is an atypical amphetamine analog that has been contraindicated in patients with a history of cardiovascular disease. We present a case of nonischemic dilated cardiomyopathy in the setting of chronic phentermine/topiramate use, which is the most likely cause of her dilated cardiomyopathy.
Keywords: amphetamine related cardiomyopathy; dilated cardiomyopathy; heart failure with reduced ejection fraction; nonischemic cardiomyopathy; phentermine/topiramate.
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