A Single-Center's Early Surgical Outcomes of Living Donor Liver Transplantation

Transplant Proc. 2023 Jun;55(5):1209-1213. doi: 10.1016/j.transproceed.2023.03.028. Epub 2023 Apr 28.

Abstract

Background: Living donor liver transplantation (LDLT) has become an increasingly common surgical option because the number of cadaveric donors is insufficient to fulfill the organ needs of patients facing end-stage cirrhosis. Many centers are investigating different surgical techniques to achieve lower complication rates. We aimed to examine our complication rates in light of demographic data, graft data, and perioperative findings as a single-center experience.

Methods: The study included one hundred and three patients who underwent LDLT for end-stage liver cirrhosis. Demographic data; sex; age; blood group; Model for End-Stage Liver Disease score; Child score; etiology; liver side; graft-to-recipient weight ratio; hepatic artery, portal vein, and bile anastomosis type rates; anhepatic phase; cold ischemia time; operation time; and blood product transfusion rates were analyzed. Biliary complications in patients with single or multiple biliary anastomoses, right or left liver transplants, and with or without hepatic artery thrombosis were analyzed statistically.

Results: There was no significant difference in biliary complications between patients who underwent single or multiple bile anastomosis (P = .231) or patients receiving right lobe and left lobe transplants (P = .315). Although there was no statistically significant difference in the rate of portal vein thrombosis between the regular and reconstructed portal vein anastomosis groups (P = .693), the postoperative portal vein thrombosis rate was statistically higher in patients with left lobe transplants (P = .044).

Conclusions: Vascular and biliary complication rates can be reduced with increasing experience.

MeSH terms

  • Anastomosis, Surgical / methods
  • Child
  • End Stage Liver Disease* / etiology
  • End Stage Liver Disease* / surgery
  • Humans
  • Liver Cirrhosis / etiology
  • Liver Cirrhosis / surgery
  • Liver Diseases* / surgery
  • Liver Transplantation* / adverse effects
  • Liver Transplantation* / methods
  • Living Donors
  • Retrospective Studies
  • Severity of Illness Index
  • Thrombosis* / etiology
  • Treatment Outcome