Esophageal papillomatosis: an exceedingly rare disease

Dandan Li; Changfeng Li; Yuxing Yan; Minya Liu

doi:10.1186/s13023-023-02703-8

Esophageal papillomatosis: an exceedingly rare disease

Orphanet J Rare Dis. 2023 Apr 29;18(1):99. doi: 10.1186/s13023-023-02703-8.

Authors

Dandan Li¹, Changfeng Li², Yuxing Yan², Minya Liu²

Affiliations

¹ Department of Gastrointestinal Medicine (Endoscopy Center), Jilin University, China-Japan Union Hospital, 126 Xiantai Street, Erdao, Changchun, 130033, People's Republic of China. lidd@jlu.edu.cn.
² Department of Gastrointestinal Medicine (Endoscopy Center), Jilin University, China-Japan Union Hospital, 126 Xiantai Street, Erdao, Changchun, 130033, People's Republic of China.

Abstract

If esophageal papilloma (EP) is a rare condition, esophageal papillomatosis (EPS) is a distinct rarity. To date, only 53 well documented cases have been described in English literature. However, the number of reports on EPS significantly increased to over 40 cases during the past 20 years. Perhaps, this is due to the broad use of endoscopy and related research achievements. Most of the cases are individual and it seems that there are no associations between them. And up to now no guidelines can be followed. To further understand this exceedingly rare disease, we had a comprehensive review of the epidemiology, etiology, clinical manifestations, pathogenesis, treatment, and clinical course of EPS.

Keywords: Endoscopy; Esophageal cancer; Esophageal papillomatosis; Human papilloma virus; Treatment.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Endoscopy
Esophageal Neoplasms* / diagnosis
Esophageal Neoplasms* / epidemiology
Esophageal Neoplasms* / etiology
Humans
Papilloma* / complications
Papilloma* / diagnosis
Papilloma* / epidemiology
Rare Diseases / complications