Cerebellar ataxia with anti-mGluR1 auto-antibody in a pediatric patient: A case report

Hongyan Wang; Bin Yi; Meng Wang; Yadan Wang; Shan Wang; Li Wang; Haixia Song; Juan Fu; Xindi Wang; Lei Cao

doi:10.1016/j.jneuroim.2023.578082

Cerebellar ataxia with anti-mGluR1 auto-antibody in a pediatric patient: A case report

J Neuroimmunol. 2023 May 15:378:578082. doi: 10.1016/j.jneuroim.2023.578082. Epub 2023 Apr 4.

Authors

Hongyan Wang¹, Bin Yi¹, Meng Wang¹, Yadan Wang¹, Shan Wang¹, Li Wang¹, Haixia Song¹, Juan Fu¹, Xindi Wang¹, Lei Cao²

Affiliations

¹ Department of Pediatrics, Gansu Provincial Maternal and Child Health Hospital/Central Hospital of Gansu Province, Lanzhou, Gansu, China.
² Department of Pediatrics, Gansu Provincial Maternal and Child Health Hospital/Central Hospital of Gansu Province, Lanzhou, Gansu, China. Electronic address: caolei20221130@163.com.

PMID: 37119682
DOI: 10.1016/j.jneuroim.2023.578082

Abstract

Cerebellar ataxia (CA) related to anti-metabolic glutamate receptor 1 (mGluR1) is a rare autoimmune encephalitis, which is manifested as acute or subacute CA in most cases.To the best of our knowledge, only three cases of pediatric patients have been reported in the literature so far. This article reports the 4th case of mGluR1 related CA in a pediatric patient.

Keywords: Alopecia areata; Ataxia; Autoimmune encephalitis; Pediatrics; mGluR1.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Autoantibodies
Cerebellar Ataxia* / drug therapy
Child
Encephalitis* / drug therapy
Hashimoto Disease*
Humans

Substances

Autoantibodies