Novel Approaches to Postnatal Prophylaxis to Eliminate Vertical Transmission of HIV

Theodore Ruel; Martina Penazzato; Jennifer M Zech; Moherndran Archary; Tim R Cressey; Ameena Goga; Joseph Harwell; Raphael J Landovitz; Maria Grazia Lain; Marc Lallemant; Eleanor Namusoke-Magongo; Irene Mukui; Sallie R Permar; Andrew J Prendergast; Roger Shapiro; Elaine J Abrams

doi:10.9745/GHSP-D-22-00401

Novel Approaches to Postnatal Prophylaxis to Eliminate Vertical Transmission of HIV

Glob Health Sci Pract. 2023 Apr 28;11(2):e2200401. doi: 10.9745/GHSP-D-22-00401. Print 2023 Apr 28.

Authors

Theodore Ruel¹, Martina Penazzato², Jennifer M Zech³, Moherndran Archary⁴, Tim R Cressey⁵, Ameena Goga^{6

7}, Joseph Harwell⁸, Raphael J Landovitz⁹, Maria Grazia Lain¹⁰, Marc Lallemant^{11

12}, Eleanor Namusoke-Magongo¹³, Irene Mukui¹⁴, Sallie R Permar¹⁵, Andrew J Prendergast^{16

17}, Roger Shapiro¹⁸, Elaine J Abrams^{3

19}

Affiliations

¹ University of California, San Francisco, San Francisco, CA, USA.
² World Health Organization, Geneva, Switzerland.
³ ICAP at Columbia University, Mailman School of Public Health, Columbia University, NY, USA.
⁴ University of KwaZulu-Natal, Durban, South Africa.
⁵ AMS-IRD Research Collaboration, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
⁶ HIV and other Infectious Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa.
⁷ Department of Paediatrics and Child Health, University of Pretoria, South Africa.
⁸ Clinton Health Access Initiative, Boston, MA, USA.
⁹ UCLA Center for Clinical AIDS Research and Education, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
¹⁰ Fundação Ariel Glaser contra o SIDA Pediátrico, Maputo, Mozambique.
¹¹ AMS-PHPT Research Collaboration, Chiang Mai University, Chiang Mia, Thailand.
¹² Penta Foundation Italy, Padova, Italy.
¹³ Paediatric and Adolescent HIV Care Treatment Branch, Ministry of Health, Kampala, Uganda.
¹⁴ Drugs for Neglected Diseases Initiative, Nairobi, Kenya.
¹⁵ Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA.
¹⁶ Queen Mary University of London, London, United Kingdom.
¹⁷ Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.
¹⁸ Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
¹⁹ Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.

Abstract

Despite progress in providing antiretroviral therapy to pregnant women living with HIV, a substantial number of vertical transmissions continue to occur. Novel approaches leveraging modern potent, safe, and well-tolerated antiretroviral drugs are urgently needed.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Anti-HIV Agents* / therapeutic use
Breast Feeding
Female
HIV Infections* / drug therapy
Humans
Infant
Infectious Disease Transmission, Vertical / prevention & control

Substances

Anti-HIV Agents

Abstract

Publication types

MeSH terms

Substances

Grants and funding