Erythema nodosum caused by goserelin acetate sustained-release: Case report and literature review

Int J Rheum Dis. 2023 Oct;26(10):2055-2059. doi: 10.1111/1756-185X.14692. Epub 2023 Apr 28.

Abstract

Goserelin acetate is a gonadotropin-releasing hormone analog that is commonly used in patients with prostate cancer, endometriosis, and precocious puberty. The side effects of the drug include allergic rash, flushing, excessive sweating, skin swelling at the injection site, sexual dysfunction, erectile dysfunction, and menopausal symptoms. However, erythema nodosum has so far not been reported. In this paper, we have presented the case of erythema nodosum caused by goserelin acetate and a review of the literature on its adverse effects, thus providing useful insights into clinical management and medication safety.

Keywords: adverse drug reactions; erythema nodosum; goserelin acetate implant.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Delayed-Action Preparations
  • Endometriosis* / chemically induced
  • Endometriosis* / drug therapy
  • Erythema Nodosum*
  • Female
  • Goserelin / adverse effects
  • Humans
  • Male

Substances

  • Goserelin
  • Delayed-Action Preparations