Potential Application of Pulsed Field Ablation in Ventricular Arrhythmias

Medicina (Kaunas). 2023 Apr 7;59(4):723. doi: 10.3390/medicina59040723.

Abstract

Pulsed field ablation (PFA) is a new ablative method for the therapy of arrhythmia. Recent preclinical and clinical studies have already demonstrated the feasibility and safety of PFA for the treatment of atrial fibrillation (AF). However, the application of PFA may not be limited to the above fields. There are some data on the application of PFA on ventricular arrhythmias (VAs), such as ventricular fibrillation (VF) and ventricular tachycardia (VT). Further, a case report about PFA has been published recently, in which PFA was successfully applied to the ablation of premature ventricular contractions (PVCs) from the right ventricular outflow tract. Thus, we aimed to review recent research findings of PFA in ventricular ablation and evaluate the possibility of its application in VAs.

Keywords: Purkinje system; coronary venous system; myocardium; pulsed field ablation; ventricular arrhythmias.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Atrial Fibrillation*
  • Catheter Ablation* / methods
  • Heart Ventricles / surgery
  • Humans
  • Tachycardia, Ventricular* / surgery
  • Treatment Outcome
  • Ventricular Premature Complexes* / surgery