Characteristics of Facilities With Early and Rapid Ustekinumab Adoption for Patients With Inflammatory Bowel Disease

Am J Gastroenterol. 2023 Sep 1;118(9):1688-1692. doi: 10.14309/ajg.0000000000002304. Epub 2023 Apr 25.

Abstract

Introduction: To examine which facility characteristics, including teamwork, are associated with early or rapid inflammatory bowel disease-related ustekinumab adoption.

Methods: We examined the association between ustekinumab adoption and the characteristics of 130 Veterans Affairs facilities.

Results: Mean ustekinumab adoption increased by 3.9% from 2016 to 2018 and was higher in urban compared with rural facilities (β = 0.03, P = 0.033) and among facilities with more teamwork (β = 0.11, P = 0.041). Compared with nonearly adopters, early adopters were more likely be high-volume facilities (46% vs 19%, P = 0.001).

Discussion: Facility variation in medication adoption provides an opportunity for improving inflammatory bowel disease care through targeted dissemination strategies to improve medication uptake.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Humans
  • Inflammatory Bowel Diseases* / drug therapy
  • Ustekinumab* / therapeutic use

Substances

  • Ustekinumab