Association of meal timing with body composition and cardiometabolic risk factors in young adults

Abstract

Purpose: To investigate the association of meal timing with body composition and cardiometabolic risk factors in young adults.

Methods: In this cross-sectional study participated 118 young adults (82 women; 22 ± 2 years old; BMI: 25.1 ± 4.6 kg/m²). Meal timing was determined via three non-consecutive 24-h dietary recalls. Sleep outcomes were objectively assessed using accelerometry. The eating window (time between first and last caloric intake), caloric midpoint (local time at which ≥ 50% of daily calories are consumed), eating jetlag (variability of the eating midpoint between non-working and working days), time from the midsleep point to first food intake, and time from last food intake to midsleep point were calculated. Body composition was determined by DXA. Blood pressure and fasting cardiometabolic risk factors (i.e., triglycerides, total cholesterol, high-density lipoprotein-cholesterol, low-density lipoprotein-cholesterol, and insulin resistance) were measured.

Results: Meal timing was not associated with body composition (p > 0.05). The eating window was negatively related to HOMA-IR and cardiometabolic risk score in men (R² = 0.348, β = - 0.605; R² = 0.234, β = - 0.508; all p ≤ 0.003). The time from midsleep point to first food intake was positively related to HOMA-IR and cardiometabolic risk score in men (R² = 0.212, β = 0.485; R² = 0.228, β = 0.502; all p = 0.003). These associations remained after adjusting for confounders and multiplicity (all p ≤ 0.011).

Conclusions: Meal timing seems unrelated to body composition in young adults. However, a longer daily eating window and a shorter time from midsleep point to first food intake (i.e., earlier first food intake in a 24 h cycle) are associated with better cardiometabolic health in young men.

Clinical trial registration: NCT02365129 ( https://www.

Clinicaltrials: gov/ct2/show/NCT02365129?term=ACTIBATE&draw=2&rank=1 ).

Keywords: Chrononutrition; Circadian rhythms; Fat mass; Insulin resistance; Intermittent fasting; Timing of food intake.