Dietary exposure to food azo-colours in a sample of pre-school children from Southern Brazil

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2023 May;40(5):613-624. doi: 10.1080/19440049.2023.2203778. Epub 2023 Apr 26.

Abstract

The dietary exposure of six food azo-colours was assessed in a sample of pre-schoolers from Guaratuba-Paraná, Brazil. Consumption data of 323 children aged 2 to 5 years was collected through 3-day food records. Dietary exposure, is expressed by milligrams of food colour by kilogram of body weight per day, as compared to the Acceptable Daily Intake (ADI). Three exposure scenarios were developed to account for uncertainties around consumption estimates. Intakes of Amaranth (INS 123) described in means, 50th and 95th percentiles exceeded ADI levels in the two most conservative scenarios, with the highest percentiles exceeding about four times the ADI. High intakes of Sunset Yellow FCF (INS 110) were also observed, of up to 85% of the ADI in the worst-case scenario. Findings suggest high exposure levels to azo-dyes in the survey population, with children likely exceeding the ADI for Amaranth (INS 123) and concerns for Sunset Yellow FCF (INS 110). Major food contributors were beverages (juice powders and soft drinks), dairy and sweets. Further studies on dietary exposure assessment are needed at the national level. The authors highlight the need of controlling the use of such additives through national policies that are aligned with the consumption patterns observed in the country.

Keywords: Additives; azo-dyes; child nutrition; exposure assessment; synthetic food colours.

MeSH terms

  • Amaranth Dye
  • Azo Compounds*
  • Brazil
  • Child
  • Child, Preschool
  • Color
  • Dietary Exposure*
  • Humans

Substances

  • 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt
  • Azo Compounds
  • Amaranth Dye