Laparoscopic sleeve gastrectomy for obesity treatment in adolescents and young adults: a systematic review and meta-analysis

Langenbecks Arch Surg. 2023 Apr 24;408(1):158. doi: 10.1007/s00423-023-02894-5.

Abstract

Background: The incidence of obesity has been increasing in younger population, posing a significant impact on adolescents' life and health care system worldwide.

Methods: We critically analyzed the existing literature on the use of laparoscopic sleeve gastrectomy (LSG) for the treatment of obesity. We performed an in-depth evaluation of 37 studies and analyzed the effect of LSG in 2300 patients, aged ≤ 22 years.

Results: Mean body mass index (BMI) loss after LSG was 17.81 kg/m2. Gastroesophageal reflux was the most common complication. Most of the patients showed remission of comorbidities including hypertension, diabetes, and obstructive sleep apnea after LSG.

Conclusions: These findings suggest that surgical intervention is highly beneficial for reducing BMI in appropriately selected adolescents and young adults suffering from obesity and comorbidities such as life-threatening obstructive sleep apnea.

Keywords: Adolescents; BMI; Laparoscopic sleeve gastrectomy; Meta-analysis; Obesity; Systematic review; Weight loss; Young adults.

Publication types

  • Meta-Analysis
  • Systematic Review

MeSH terms

  • Adolescent
  • Body Mass Index
  • Gastrectomy* / adverse effects
  • Humans
  • Laparoscopy* / adverse effects
  • Obesity / complications
  • Obesity, Morbid* / surgery
  • Retrospective Studies
  • Sleep Apnea, Obstructive / complications
  • Sleep Apnea, Obstructive / surgery
  • Treatment Outcome
  • Young Adult