An integrative analysis of the single-cell transcriptome identifies DUSP4 as an exhaustion-associated gene in tumor-infiltrating CD8+ T cells

Funct Integr Genomics. 2023 Apr 22;23(2):136. doi: 10.1007/s10142-023-01056-6.

Authors

Yu Zhao¹, Huihui Cai¹, Xiaoling Ding^{2

3}, Xiaorong Zhou⁴

Affiliations

¹ Department of Immunology, Nantong University, School of Medicine, Nantong, China.
² Department of Immunology, Nantong University, School of Medicine, Nantong, China. dixili@126.com.
³ Department of Gastroenterology, The Affiliated Hospital of Nantong University, Nantong, China. dixili@126.com.
⁴ Department of Immunology, Nantong University, School of Medicine, Nantong, China. zhouxiaorong@ntu.edu.cn.

PMID: 37086337
DOI: 10.1007/s10142-023-01056-6

No abstract available

Publication types

Letter

MeSH terms

CD8-Positive T-Lymphocytes* / metabolism
Dual-Specificity Phosphatases* / genetics
Humans
Mitogen-Activated Protein Kinase Phosphatases
Neoplasms* / genetics
Single-Cell Gene Expression Analysis
Transcriptome*

Substances

Dual-Specificity Phosphatases
DUSP4 protein, human
Mitogen-Activated Protein Kinase Phosphatases