Lung Transplantation in Coronavirus-19 Patients: What We Have Learned So Far

Clin Chest Med. 2023 Jun;44(2):347-357. doi: 10.1016/j.ccm.2022.11.017. Epub 2022 Nov 22.

Abstract

Coronavirus-19 (COVID-19) can result in irrecoverable acute respiratory distress syndrome (ARDS) or life-limiting fibrosis for which lung transplantation is currently the only viable treatment. COVID-19 lung transplantation has transformed the field of lung transplantation, as before the pandemic, few transplants had been performed in the setting of infectious disease or ARDS. Given the complexities associated with COVID-19 lung transplantation, it requires strict patient selection with an experienced multidisciplinary team in a high-resource hospital setting. Current short-term outcomes of COVID-19 lung transplantation are promising. However, follow-up studies are needed to determine long-term outcomes and whether these patients may be predisposed to unique complications.

Keywords: Acute respiratory distress syndrome; COVID-19; Lung transplantation evaluation.

Publication types

  • Review
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • COVID-19*
  • Follow-Up Studies
  • Humans
  • Lung Transplantation*
  • Respiratory Distress Syndrome* / surgery
  • SARS-CoV-2