Aggregation-Induced Emission Macromolecular Materials for Antibacterial Applications

Macromol Rapid Commun. 2023 Jul;44(13):e2300104. doi: 10.1002/marc.202300104. Epub 2023 May 5.

Abstract

Recent advancements in aggregation-induced emission (AIE) macromolecular materials have brought their attention as potential antibacterial solutions, these materials offer new approaches to cure multidrug-resistant infections and biofilms in bacterial infections as well as real-time monitoring and specific targeting of bacteria. This review provides an overview of the three main categories of AIE macromolecular materials with antibacterial properties; namely AIE-active polymers, AIEgen@polymer complexes, and clusterization-triggered emission (CTE) based polymers. The mechanisms and applications of these materials in antibacterial treatment, wound care, and protective equipment are also discussed. The potential for future developments and application directions of AIE-based antimicrobial materials are finally highlighted.

Keywords: aggregation-induced emission; antibacterial materials; bactericidal processes; polymers; therapy.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents* / pharmacology
  • Bacteria
  • Macromolecular Substances / pharmacology
  • Polymers* / pharmacology

Substances

  • Macromolecular Substances
  • Polymers
  • Anti-Bacterial Agents