Efficacy of kangaroo mother care combined with neonatal phototherapy in newborns with non-pathological jaundice: A meta-analysis

Xiang Huang; Meiling Chen; Rongrong Fu; Wei He; Yujing He; Haojie Shentu; Suping Zhu

doi:10.3389/fped.2023.1098143

Efficacy of kangaroo mother care combined with neonatal phototherapy in newborns with non-pathological jaundice: A meta-analysis

Front Pediatr. 2023 Jan 25:11:1098143. doi: 10.3389/fped.2023.1098143. eCollection 2023.

Authors

Xiang Huang¹, Meiling Chen², Rongrong Fu³, Wei He⁴, Yujing He⁵, Haojie Shentu⁶, Suping Zhu¹

Affiliations

¹ Department of Pediatric, Ningbo Yinzhou No. 2 Hospital, Ningbo, China.
² The Public Health College, Zhejiang Chinese Medical University, Hangzhou, China.
³ The First Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.
⁴ State Key Laboratory Breeding Base of Green Chemistry Synthesis Technology, Zhejiang University of Technology, Hangzhou, China.
⁵ The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.
⁶ The Medical Imaging College, Hangzhou Medical College, Hangzhou, China.

Abstract

Background: The kangaroo-mother care method (KMC) is a skin-to-skin contact-centered care approach with numerous benefits for neonates, but its impact on the treatment of jaundiced neonates is unknown. This study aimed to investigate the efficacy of KMC combined with neonatal phototherapy (NNPT) in treating neonates with non-pathological jaundice.

Methods: Relevant articles were searched in PubMed, Embase, Web of Science, and Cochrane Library databases from database establishment to April 2022. The outcomes included, without limitation, serum bilirubin levels, and duration of phototherapy.

Results: This meta-analysis included five studies (4 randomized controlled trials and 1 observational study) involving four hundred eighty-two neonates with non-pathological jaundice. The results showed that the group receiving KMC combined with NNPT had lower serum bilirubin at 72 h after intervention [weighted mean difference (WMD) = -1.51, p = 0.03], shorter duration of phototherapy [standard mean difference (SMD) = -1.45, p < 0.001] and shorter duration of hospitalization (SMD = -1.32, p = 0.002) compared to NNPT group. There was no difference in peak bilirubin in both groups of neonates (WMD = -0.12, p = 0.62).

Conclusions: KMC combined with NNPT helped to treat non-pathological jaundice in newborns compared to NNPT alone.

Keywords: hyperbilirubinemia; infant; kangaroo-Mother care method; meta—analysis; phototherapy; skin-to-skin contact.

Publication types

Review