The Spectrum of COVID-19-Induced Liver Injury in Various Age and Risk Groups

Tapasya Bhusal; Prakash Banjade; Salim Surani; Munish Sharma

doi:10.7759/cureus.36349

The Spectrum of COVID-19-Induced Liver Injury in Various Age and Risk Groups

Cureus. 2023 Mar 19;15(3):e36349. doi: 10.7759/cureus.36349. eCollection 2023 Mar.

Authors

Tapasya Bhusal¹, Prakash Banjade², Salim Surani^{3

4

5

6}, Munish Sharma⁷

Affiliations

¹ General Medicine, Shahid Dharmabhakta National Transplant Center, Kathmandu, NPL.
² General Medicine, Manipal College of Medical Sciences, Pokhara, NPL.
³ Medicine, Texas A&M University, College Station, USA.
⁴ Medicine, University of North Texas, Dallas, USA.
⁵ Internal Medicine, Pulmonary Associates, Corpus Christi, USA.
⁶ Clinical Medicine, University of Houston, Houston, USA.
⁷ Pulmonary and Critical Care, Baylor Scott & White Medical Center - Temple, Temple, USA.

Abstract

Coronavirus disease 2019 (COVID-19) has inflicted significant mortality and morbidity worldwide since the virus was first detected towards the end of 2019. Though it primarily affects the respiratory system, COVID-19 has been shown to have a multisystem effect. There have been literature on liver injury associated with COVID-19 in general but liver injury specific to certain risk and age groups needs to be looked into. Thus, we aim to discuss the liver injury associated with COVID-19 in various age and risk groups and revisit pathophysiology, biochemical markers and their correlation with outcomes, and current management recommendations.

Keywords: alanine transaminase; aspartate transaminase; coronavirus disease-2019; liver disease; liver enzyme; sars-cov-2 infection liver injury in covid-19.

Publication types

Review