Translation and cultural adaptation of MedStopper®-A web-based decision aid for deprescribing in older adults: A protocol

PLoS One. 2023 Apr 20;18(4):e0284464. doi: 10.1371/journal.pone.0284464. eCollection 2023.

Abstract

Background: Older patients are more likely to have medication-related problems, which are associated with changes in pharmacokinetics and pharmacodynamics, multimorbidity, and polypharmacy. Polypharmacy and inappropriate prescribing are well-known risk factors which commonly cause adverse clinical outcomes in older people. Prescribers struggle to identify potentially inappropriate medications and to choose an adequate tapering approach.

Methods/design: The goal of the study is to translate and culturally adapt MedStopper®, an original English language web-based decision aid system in deprescribing medication, to the Portuguese population. A translation-back translation method, with validation of the obtained Portuguese version of MedStopper® will be used, followed by a comprehension test.

Discussion: This is the first research in the Portuguese primary care setting that aims to provide a useful online tool for the appropriate prescription of older patients. The translated version in Portuguese version of the MedStopper® tool will represent an advance that seeks to continue improving the management of medications in the elderly. The adaptation into Portuguese of the educational tool provides clinicians with a screening tool to detect potentially inappropriate prescribing in patients older than 65 that reliable and easier to use.

Trial registration: Retrospectively registered.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Decision Support Techniques
  • Deprescriptions*
  • Humans
  • Inappropriate Prescribing / prevention & control
  • Internet
  • Polypharmacy
  • Potentially Inappropriate Medication List

Grants and funding

Fundação para a Ciência e Tecnologia, I.P. within CINTESIS, R&D Unit (reference UIDB/4255/2020). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."