Global trend and future landscape of coronary microcirculation: A bibliometric and visualized analysis from 1990 to 2021

Hao Ling; Sunjing Fu; Mengting Xu; Bing Wang; Yuan Li; Bingwei Li; Qin Wang; Xueting Liu; Xiaoyan Zhang; Ailing Li; Mingming Liu

doi:10.1016/j.heliyon.2023.e14894

Global trend and future landscape of coronary microcirculation: A bibliometric and visualized analysis from 1990 to 2021

Heliyon. 2023 Mar 28;9(4):e14894. doi: 10.1016/j.heliyon.2023.e14894. eCollection 2023 Apr.

Authors

Hao Ling¹, Sunjing Fu², Mengting Xu², Bing Wang², Yuan Li², Bingwei Li², Qin Wang², Xueting Liu², Xiaoyan Zhang², Ailing Li², Mingming Liu^{2

3}

Affiliations

¹ Department of Radiology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha 410004, China.
² Institute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China.
³ Diabetes Research Center, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China.

Abstract

Background: Coronary microcirculation has a fundamental role in the regulation of coronary blood flow in response to cardiac requirements, which has aroused wide concerns in basic science and clinical cardiovascular research. We aimed to analyze coronary microcirculation-associated literatures over 30 years and provide insightful information on the evolutionary path, frontier research hotspots, and future developmental trends.

Methods: Publications were retrieved from the Web of Science Core Collection (WoSCC). VOSviewer was used to perform co-occurrence analyses for countries, institutions, authors, and keywords and to generate visualized collaboration maps. CiteSpace was used to visualize the knowledge map derived from reference co-citation analysis, burst references, and keywords detection.

Results: This analysis was performed based on 11,702 publications including 9981 articles and 1721 reviews. The United States and Harvard University ranked at the top among all the countries and institutions. The majority of articles were published in Circulation, and it also was the most co-cited journal. Thematic hotspots and frontiers were focused on coronary microvascular dysfunction, magnetic resonance imaging, fractional flow reserve, STEMI, and heart failure. Additionally, keywords burst and co-occurrence cluster analysis showed that management, microvascular dysfunction, microvascular obstruction, prognostic value, outcomes, and guidelines were current knowledge gaps and future directions.

Conclusions: Coronary microcirculation presented a research hotspot relevant wide spectrum of cardiovascular diseases. Definite diagnostics and prognostics are particularly valued. The protection of cardiovascular events that influence clinical outcomes should be an insightful concern in the future. Multidisciplinary collaborations will provide significant advances for the development of coronary microcirculation.

Keywords: Bibliometric analysis; Coronary microcirculation; Diagnosis; Management; Visualization.