Complete Genome Sequence of Soil Bacterium Burkholderia sp. Strain FERM BP-3421, a Producer of Spliceostatins

Sylvia Kunakom; Barbara I Adaikpoh; Tuan Anh Tran; Alessandra S Eustáquio

doi:10.1128/mra.00111-23

Complete Genome Sequence of Soil Bacterium Burkholderia sp. Strain FERM BP-3421, a Producer of Spliceostatins

Microbiol Resour Announc. 2023 May 17;12(5):e0011123. doi: 10.1128/mra.00111-23. Epub 2023 Apr 19.

Authors

Sylvia Kunakom^{1

2}, Barbara I Adaikpoh^{1

2}, Tuan Anh Tran^{1

2}, Alessandra S Eustáquio^{1

2}

Affiliations

¹ Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA.
² Center for Biomolecular Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA.

Abstract

Here, we report the complete genome sequence of Burkholderia sp. strain FERM BP-3421, a bacterium isolated previously from a soil sample in Japan. Strain FERM BP-3421 produces spliceostatins, which are splicing modulatory antitumor agents that advanced to preclinical development. The genome is composed of four circular replicons of 3.90, 3.0, 0.59, and 0.24 Mbp.

Abstract

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