Are some mutations more equal than others?

Elife. 2023 Apr 19:12:e87194. doi: 10.7554/eLife.87194.

Authors

Auden Cote-L'Heureux¹, Yogesh N K Maithania¹, Melissa Franco¹, Konstantin Khrapko¹

Affiliation

¹ Department of Biology, Northeastern University, Boston, United States.

Abstract

A large-scale study of mutations in mitochondrial DNA has revealed a subset that do not accumulate with age.

Keywords: aging; duplex sequencing; genetics; genomics; mitochondrial DNA; mouse; somatic mutations.

© 2023, Cote-L’, Cote-L’, Cote-L’Heureux et al.

Publication types

Comment

MeSH terms

DNA, Mitochondrial* / genetics
Mitochondria* / genetics
Mutation

Substances

DNA, Mitochondrial