How can we improve the measurement of receptor signaling bias?

Karim Nagi

doi:10.1080/17460441.2023.2204225

How can we improve the measurement of receptor signaling bias?

Expert Opin Drug Discov. 2023 Jun;18(6):575-578. doi: 10.1080/17460441.2023.2204225. Epub 2023 Apr 19.

Author

Karim Nagi¹

Affiliation

¹ College of Medicine, QU Health, Qatar University, Doha, Qatar.

PMID: 37073510
DOI: 10.1080/17460441.2023.2204225

No abstract available

Keywords: Biased agonism; Biased ligand; Drug discovery; Functional selectivity; GPCR; Receptor signaling; Screening; Signaling bias; Signaling pathways.

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Bias
Humans
Ligands
Receptors, G-Protein-Coupled*
Signal Transduction*

Substances

Receptors, G-Protein-Coupled
Ligands