Warthin-like papillary carcinoma: Case report

Cesk Patol. 2023 Spring;59(1):23-25.

Abstract

Warthin-like papillary thyroid carcinoma is a rare variant of papillary carcinoma with a very good prognosis. It is often associated with lymphocytic thyroiditis. Due to its typical histological picture resembling Warthin's salivary gland tumor, the histological diagnosis is not difficult, usually does not require an accompanying immunohistochemical examination and is based on the presence of nuclear features typical of papillary carcinoma and the presence of oncocytes in a background of rich lymphocyte infiltrate. The preoperative cytologic examination is challenging, as many other lesions may have a similar picture. Women are more likely to get affected. It appears a decade earlier than the classic variant. Clinically, it presents similarly to a conventional papillary carcinoma. In our case report, we would like to present the case of a 56-year-old woman with non-toxic multinodular goiter, in whom the presence of this rare variant of papillary carcinoma was revealed by histological examination.

Keywords: Thyroid; Warthin-like papillary carcinoma; oncocytes; papillary carcinoma; thyroid gland.

Publication types

  • Case Reports

MeSH terms

  • Adenolymphoma* / diagnosis
  • Adenolymphoma* / pathology
  • Adenolymphoma* / surgery
  • Carcinoma, Papillary* / diagnosis
  • Carcinoma, Papillary* / pathology
  • Carcinoma, Papillary* / surgery
  • Female
  • Humans
  • Middle Aged
  • Prognosis
  • Thyroid Neoplasms* / diagnosis