Au → M bonds promote catalytic alkyne hydrofunctionalisation

M Alexander Eltester; Hans Gildenast; Kristína Rabatinová; Christopher Pütz; Christopher Cremer; Patrick Lanzerath; Julian P Schroers; Michael E Tauchert

doi:10.1039/d3cc01008b

Au → M bonds promote catalytic alkyne hydrofunctionalisation

Chem Commun (Camb). 2023 May 2;59(36):5459-5462. doi: 10.1039/d3cc01008b.

Authors

M Alexander Eltester¹, Hans Gildenast¹, Kristína Rabatinová¹, Christopher Pütz¹, Christopher Cremer¹, Patrick Lanzerath¹, Julian P Schroers¹, Michael E Tauchert¹

Affiliation

¹ Institute of Inorganic Chemistry, RWTH Aachen University, Landoltweg 1, Aachen D-52074, Germany. Michael.Tauchert@ac.rwth-aachen.de.

PMID: 37070595
DOI: 10.1039/d3cc01008b

Abstract

The impact of metalloligands on Au catalysed alkyne hydrofunctionalisation is studied. Ambiphilic PMP-type ligands (M = Cu^I, Ag^I, Zn^II) stabilise Au → M bonds including unprecedented Au^I → Zn^II interactions. The Lewis acidity of Au increases in the order Cu^I < Ag^I < Zn^II promoting catalytic cycloisomerisation of propargylamide 14. Au/Zn complex 8 is an excellent catalyst for alkyne hydroamination.