A Case Report of a Kidney Transplant Recipient With Organizing Pneumonia After Graft Loss

Transplant Proc. 2023 May;55(4):1081-1083. doi: 10.1016/j.transproceed.2023.03.023. Epub 2023 Apr 15.

Abstract

We present a case of a 68-year-old male patient who underwent ABO-incompatible living kidney transplantation from his wife because of immunoglobulin A nephropathy 13 years ago. Over time, the patient showed a gradual decline in graft function and required reinitiation of hemodialysis because of fluid overload, which led to his admission to our hospital. An arteriovenous fistula was created, and subsequently, hemodialysis therapy was started. Because he had chronic cytomegalovirus retinopathy and thrombotic microangiopathy due to immunosuppressive therapy at admission, mycophenolate mofetil and tacrolimus were discontinued during hemodialysis initiation. Only low-dose prednisolone was continued. One week later, the patient had a fever, and chest computed tomography revealed bilateral pneumonia, which was not improved by antibiotics. The patient was diagnosed with organized pneumonia. After ruling out opportunistic infection, including pneumocystis pneumonia, increased doses of prednisolone resulted in the remission of organizing pneumonia.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Graft Rejection
  • Humans
  • Immunosuppressive Agents / adverse effects
  • Kidney Transplantation* / adverse effects
  • Male
  • Organizing Pneumonia*
  • Pneumonia*
  • Prednisolone / therapeutic use

Substances

  • Immunosuppressive Agents
  • Prednisolone