A New Look at Structural Changes in the Aortic Root in Aortic Valve Stenosis

Sovrem Tekhnologii Med. 2022;14(2):51-56. doi: 10.17691/stm2022.14.2.05. Epub 2022 Mar 28.

Abstract

The aim of the study was to identify new anatomical landmarks of the aortic root and the relationship between the sizes of anatomical structures using the method of computed tomography angiography to improve models of heart valves and the methods for their selection in clinical practice.

Materials and methods: The dataset of computed tomography angiography prior to aortic valve replacement in 262 patients was analyzed. The mean age was 75.0±5.9 years. 99 (37.8±3.0%) men and 163 (62.2±3.0%) women took part in the study. The annulus fibrosus, sinotubular junction, and height of the sinuses of Valsalva were measured.

Results: In the tricuspid aortic valve group (n=251), in more than 50% of the cases, the diameter of the annulus fibrosus ranged from 23 to 26 mm. No significant association between the diameter of the annulus fibrosus and patient height (r=0.35; p=0.01) or body surface area (r=0.25; p=0.01) and the height of the sinuses of Valsalva (r=0.34; p=0.01) were revealed. Based on the ratio of the height of the sinuses of Valsalva and the diameter of the annulus fibrosus, three variants of the structure of the aortic root were identified: type A - K>1.05; type B- 0.95≤K≤1.05; type C- K<0.95. Type C of the aortic root was found to predominate in most cases, namely, in 98.0±0.9% (n=246).In the bicuspid aortic valve group (n=11), 2 patients had a type A of the aortic root, 1 patient had a type B, and 8 patients had a type C.

Conclusion: A classification of variants of the aortic root structure has been proposed, which will be useful not only for practitioners when choosing a treatment method, but also for researchers to understand the structural characteristics of the aortic root in patients with its pathology.

Keywords: 3D modeling of the aortic root; aortic stenosis; aortic valve; computed tomography; transcatheter aortic valve implantation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aorta / diagnostic imaging
  • Aorta / pathology
  • Aorta, Thoracic* / pathology
  • Aortic Valve / diagnostic imaging
  • Aortic Valve / pathology
  • Aortic Valve Stenosis* / diagnostic imaging
  • Aortic Valve Stenosis* / pathology
  • Aortic Valve Stenosis* / surgery
  • Female
  • Humans
  • Male
  • Tomography, X-Ray Computed / methods

Grants and funding

Study funding. The research was carried out within the state assignment of Ministry of Health of the Russian Federation (Development of tissue-engineered structures for cardiovascular surgery/N: 121032300337-5).