Effects of dietary adenosine and adenosine 5'-monophosphate supplementation on carcass characteristics, meat quality, and lipid metabolism in adipose tissues of finishing pigs

Sujuan Rao; Zhijuan Cui; Longmiao Zhang; Shuo Ma; Shuangbo Huang; Li Feng; Yiling Chen; Jinxi Luo; Jinfeng Li; Shiyu Qian; Hanting Liu; Yanzhi Liu; Linfang Yang; Yulong Yin; Chengquan Tan

doi:10.1016/j.meatsci.2023.109174

Effects of dietary adenosine and adenosine 5'-monophosphate supplementation on carcass characteristics, meat quality, and lipid metabolism in adipose tissues of finishing pigs

Meat Sci. 2023 Jul:201:109174. doi: 10.1016/j.meatsci.2023.109174. Epub 2023 Mar 26.

Authors

Sujuan Rao¹, Zhijuan Cui¹, Longmiao Zhang¹, Shuo Ma¹, Shuangbo Huang¹, Li Feng¹, Yiling Chen¹, Jinxi Luo¹, Jinfeng Li¹, Shiyu Qian¹, Hanting Liu¹, Yanzhi Liu², Linfang Yang², Yulong Yin³, Chengquan Tan⁴

Affiliations

¹ Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, Institute of Subtropical Animal Nutrition and Feed, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
² Guangdong Yihao Local Pig Research Institute Co., Ltd., Zhanjiang, Guangdong 524000, China.
³ Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, Institute of Subtropical Animal Nutrition and Feed, College of Animal Science, South China Agricultural University, Guangzhou 510642, China; National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, 410125, Hunan, China.
⁴ Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, Institute of Subtropical Animal Nutrition and Feed, College of Animal Science, South China Agricultural University, Guangzhou 510642, China. Electronic address: tanchengquan@scau.edu.cn.

PMID: 37054497
DOI: 10.1016/j.meatsci.2023.109174

Abstract

This study investigated the effects of adenosine (ADO) and adenosine 5'-monophosphate (AMP) supplementation on the growth performance, carcass characteristics, meat quality, and lipid metabolism in adipose tissues of finishing pigs. The pigs were allocated to three treatment groups: the control diet, 0.2%ADO diet, or 0.2%AMP diet. Compared with CON group (CON), both ADO and AMP groups increased in carcass straight length (P < 0.05) and decreased in drip loss (P < 0.05), while AMP group tended to increase in redness value (P = 0.05) and decreased in free amino acid content in longissimus thoracis (LT) muscle (P < 0.05). Additionally, ADO or AMP supplementation increased the ADO or AMP content in serum, adipose tissue, and LT muscle (P < 0.05), as well as the protein level of adenosine 2A receptor (A2a) in adipose tissue (P < 0.05). Moreover, both ADO and AMP groups showed an increase in the expression of lipolysis genes (ATGL and HSL) in adipose tissue (P < 0.05). Overall, AMP supplementation could improve meat quality, and ADO and AMP supplementation regulate the lipid metabolism of finishing pigs.

Keywords: ADO; AMP; Amino acids; Carcass traits; Growth performance; Lipid metabolism; Meat quality.

MeSH terms

Adipose Tissue / chemistry
Animal Feed / analysis
Animals
Body Composition*
Diet / veterinary
Dietary Supplements
Lipid Metabolism*
Meat / analysis
Swine