Carbon Nanomaterials: Emerging Roles in Immuno-Oncology

Int J Mol Sci. 2023 Apr 1;24(7):6600. doi: 10.3390/ijms24076600.

Abstract

Cancer immunotherapy has made breakthrough progress in cancer treatment. However, only a subset of patients benefits from immunotherapy. Given their unique structure, composition, and interactions with the immune system, carbon nanomaterials have recently attracted tremendous interest in their roles as modulators of antitumor immunity. Here, we focused on the latest advances in the immunological effects of carbon nanomaterials. We also reviewed the current preclinical applications of these materials in cancer therapy. Finally, we discussed the challenges to be overcome before the full potential of carbon nanomaterials can be utilized in cancer therapies to ultimately improve patient outcomes.

Keywords: cancer; carbon nanomaterials; immunotherapy.

Publication types

  • Review

MeSH terms

  • Carbon / chemistry
  • Carbon / therapeutic use
  • Humans
  • Immunotherapy
  • Medical Oncology
  • Nanostructures* / chemistry
  • Nanostructures* / therapeutic use
  • Neoplasms* / therapy

Substances

  • Carbon