Post-rhinoplasty complications with previous hyaluronic acid injection history: Cerebral infarction and vision loss

J Cosmet Dermatol. 2023 Oct;22(10):2677-2681. doi: 10.1111/jocd.15775. Epub 2023 Apr 12.

Abstract

Background: Rhinoplasty is becoming increasingly frequent as the pursuit of aesthetics by people accelerates. In recent years, the proportion of people opting for rhinoplasty injections has gradually increased. This has led to numerous reports citing catastrophic postoperative complications such as skin necrosis, cerebral infarction, and visual impairment.

Aim: The aim of our report is to discuss the possible etiological factors for this post-rhinoplasty complication and provides a rationale for HA injection history as a risk factor in rhinoplasty.

Methods: We report a rare case that received nasal HA injections in the past without any untoward incident. She opted for a second rhinoplasty 2 years after her initial nasal HA injections. This second intervention led to post-injection loss of vision in one eye and cerebral infarction. Following clinical and radiological examination, digital subtraction angiography (DSA) and superselective intra-arterial thrombolysis were performed.

Results: The patient did not develop disuse exotropia or ocular atrophy, but the left eye remained without light perception, which implies that intra-arterial thrombolytic therapy may be a positive and effective method to maintain the normal appearance of the eye.

Conclusion: It is advisable for patient safety to maintain a long interval of time between hyaluronidase injection and repeat rhinoplasty. Clinicians should become familiar with the anatomical peculiarities of the patient and be gentle during the rhinoplasty procedure.

Keywords: angioembolic complications; central retinal artery embolism; hyaluronic acid; rhinoplasty.

Publication types

  • Case Reports

MeSH terms

  • Cerebral Infarction / diagnostic imaging
  • Cerebral Infarction / etiology
  • Dermal Fillers* / adverse effects
  • Female
  • Humans
  • Hyaluronic Acid / adverse effects
  • Injections
  • Rhinoplasty* / adverse effects
  • Rhinoplasty* / methods
  • Vision Disorders

Substances

  • Hyaluronic Acid
  • Dermal Fillers