Efficacy of hydrogen peroxide to reduce Gyrodactylus species infestation density on four fish species

J Aquat Anim Health. 2023 Jun;35(2):64-77. doi: 10.1002/aah.10179. Epub 2023 Apr 11.

Abstract

Objective: The ability to effectively treat parasitic infestations of fish is of high importance for fish culture facilities. However, tools or approved therapies for treating infestations on fish are limited. This paper summarizes results from four separate clinical field studies that evaluated the efficacy of hydrogen peroxide (H2 O2 ; 35% PEROX-AID) for reducing Gyrodactylus spp. infestation density.

Methods: Three species of Gyrodactylus were studied (G. salmonis, hosts: Brook Trout Salvelinus fontinalis and Lake Trout S. namaycush; G. freemani, host: Yellow Perch Perca flavescens; G. hoffmani, host: Fathead Minnow Pimephales promelas) before and after the application of immersion H2 O2 therapy.

Result: Parasite density was significantly reduced for each parasite × host combination to which H2 O2 therapy was applied. Two clinical field studies in salmonids were found to demonstrate substantial effectiveness that enabled 35% PEROX-AID approval.

Conclusion: Further assessments of Gyrodactylus spp. could expand the use of H2 O2 for controlling these parasites in aquaculture. Specifically, H2 O2 was effective at all levels tested (50 or 75 mg H2 O2 /L for 60 min for the Yellow Perch and Fathead Minnow clinical field studies; 100 or 150 mg H2 O2 /L for 30 min regardless of salt pre-treatment for the Brook Trout study; and 100 mg H2 O2 /L for 30 min or 50 mg H2 O2 /L for 60 min for the Lake Trout study).

Keywords: Gyrodactylus; Brook Trout; Fathead Minnow; Lake Trout; Yellow Perch; hydrogen peroxide; treatment.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Cyprinidae*
  • Fish Diseases* / drug therapy
  • Fish Diseases* / parasitology
  • Hydrogen Peroxide
  • Perches*
  • Salmonidae* / parasitology
  • Trematoda*
  • Trout

Substances

  • Hydrogen Peroxide