What are the optimal first-line therapies for patients with microsatellite instability-high/mismatch repair-deficient metastatic colorectal cancer?

Ann Palliat Med. 2023 May;12(3):607-610. doi: 10.21037/apm-22-1391. Epub 2023 Mar 2.

Authors

Koichi Taira¹, Akie Kimura¹, Akinobu Nakata¹, Fumio Tanaka¹, Yasuaki Nagami¹, Yasuhiro Fujiwara¹

Affiliation

¹ Department of Gastroenterology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.

PMID: 37038074
DOI: 10.21037/apm-22-1391

No abstract available

Keywords: Immunotherapy; colorectal cancer (CRC); first-line treatment.

MeSH terms

Colonic Neoplasms*
Colorectal Neoplasms* / drug therapy
Colorectal Neoplasms* / genetics
Colorectal Neoplasms* / pathology
DNA Mismatch Repair
Humans
Microsatellite Instability

Supplementary concepts

Turcot syndrome