Relapse of Non-Gastrointestinal Langerhans Cell Histiocytosis in the Rectum in a Child: A Case Report

Saad Muhammad Saeed; Sundus Bilal; Asif Loya; Muhammed Aasim Yusuf

doi:10.1177/11795476231163961

Relapse of Non-Gastrointestinal Langerhans Cell Histiocytosis in the Rectum in a Child: A Case Report

Clin Med Insights Case Rep. 2023 Apr 2:16:11795476231163961. doi: 10.1177/11795476231163961. eCollection 2023.

Authors

Saad Muhammad Saeed¹, Sundus Bilal¹, Asif Loya¹, Muhammed Aasim Yusuf¹

Affiliation

¹ Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Punjab, Pakistan.

Abstract

Langerhans cell histiocytosis (LCH) is a rare disorder most commonly involving skin, bone and lung. The gastrointestinal tract (GIT) is an uncommon site of disease and only a handful of case reports exist. We present a case of a 15-year old boy with treated LCH involving the skin, bones, central nervous system (CNS) and pituitary gland. He presented with rectal bleeding and on investigation was found to have a single rectal polyp which was confirmed histologically and immunologically to be LCH. Further investigation revealed no other foci of disease.

Keywords: Case report; LCH; Langerhans cell histiocytosis; paediatric cancer; rectal polyps.

Publication types

Case Reports