Inflammatory Hepatocellular Adenoma Mimicking Focal Nodular Hyperplasia That Grew during Pregnancy and Changed Its Appearance on Magnetic Resonance Imaging after Delivery

Intern Med. 2023 Nov 1;62(21):3143-3149. doi: 10.2169/internalmedicine.0967-22. Epub 2023 Apr 7.

Abstract

We reported a notable case of inflammatory hepatocellular adenoma that grew during pregnancy, consequently changing its appearance on magnetic resonance imaging remarkably. A 5-months-pregnant 35-year-old woman presented with a 37-mm liver nodule that had been diagnosed as focal nodular hyperplasia 3 years earlier. She had never used oral contraceptives. After 2 months, the nodule grew to 57 mm. The patient delivered a full-term infant without complications. Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging performed after delivery revealed markedly different findings compared with the first images. A liver biopsy was performed, and the tumor was diagnosed as inflammatory hepatocellular adenoma.

Keywords: hepatocellular adenoma; magnetic resonance imaging; pregnancy; ultrasonography.

Publication types

  • Case Reports

MeSH terms

  • Adenoma, Liver Cell* / diagnostic imaging
  • Adenoma, Liver Cell* / pathology
  • Adult
  • Carcinoma, Hepatocellular* / pathology
  • Contrast Media
  • Diagnosis, Differential
  • Female
  • Focal Nodular Hyperplasia* / diagnostic imaging
  • Focal Nodular Hyperplasia* / pathology
  • Humans
  • Hyperplasia / pathology
  • Liver / diagnostic imaging
  • Liver / pathology
  • Liver Neoplasms* / pathology
  • Magnetic Resonance Imaging
  • Pregnancy

Substances

  • Contrast Media