Uncovering biology by single-cell proteomics

M Shahid Mansuri; Kenneth Williams; Angus C Nairn

doi:10.1038/s42003-023-04635-2

Uncovering biology by single-cell proteomics

Commun Biol. 2023 Apr 8;6(1):381. doi: 10.1038/s42003-023-04635-2.

Authors

M Shahid Mansuri¹, Kenneth Williams¹, Angus C Nairn²

Affiliations

¹ Yale/NIDA Neuroproteomics Center and Department of Molecular Biophysics and Biochemistry, Yale School of Medicine, New Haven, Connecticut, USA.
² Yale/NIDA Neuroproteomics Center and Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA. angus.nairn@yale.edu.

Abstract

Recent technological advances have opened the door to single-cell proteomics that can answer key biological questions regarding how protein expression, post-translational modifications, and protein interactions dictate cell state in health and disease.

Publication types

Review
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Protein Processing, Post-Translational*
Proteomics*

Grants and funding

P30 DA018343/DA/NIDA NIH HHS/United States